AirHint found the following cheapest return flights from Madrid (MAD) to Prague (PRG) in November 2025 (see full year).

Return flights

15 Nov - 20 Nov	Ryanair
15 Nov - 22 Nov	Ryanair
28 Nov - 04 Dec	Ryanair
16 Nov - 20 Nov	Ryanair
14 Nov - 19 Nov	Ryanair
16 Nov - 19 Nov	Ryanair
24 Nov - 27 Nov	Ryanair
25 Nov - 04 Dec	Ryanair	direct
26 Nov - 04 Dec	Ryanair	direct
24 Nov - 29 Nov	Ryanair
12 Nov - 20 Nov	Ryanair	direct
29 Nov - 04 Dec	Wizz Air Malta
20 Nov - 04 Dec	Ryanair	direct
15 Nov - 19 Nov	Ryanair
23 Nov - 27 Nov	Ryanair
30 Nov - 04 Dec	Ryanair
21 Nov - 04 Dec	Ryanair	direct
15 Nov - 04 Dec	Ryanair	direct
22 Nov - 04 Dec	Ryanair	direct
19 Nov - 04 Dec	Ryanair	direct

Also check the deals for one-way flights from Madrid to Prague in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Prague in November from 119€

Return flights