AirHint found the following cheapest return flights from Madrid (MAD) to Osaka (KIX) in September 2025 (see full year).

Return flights

02 Sep - 07 Sep	Air France
02 Sep - 21 Sep	Air France
04 Sep - 17 Sep	Hainan Airlines
17 Sep - 07 Oct	Ryanair
07 Sep - 17 Sep	Hainan Airlines
09 Sep - 24 Sep	Etihad Airways
01 Sep - 07 Sep	Air France
01 Sep - 14 Sep	Air France
01 Sep - 21 Sep	Air France
01 Sep - 30 Sep	Etihad Airways
08 Sep - 30 Sep	Etihad Airways
25 Sep - 14 Oct	Hainan Airlines
28 Sep - 14 Oct	Sichuan Airlines
20 Sep - 11 Oct	Ryanair
02 Sep - 07 Oct	Air France
25 Sep - 25 Oct	Hainan Airlines
13 Sep - 03 Oct	Air China
15 Sep - 08 Oct	Ryanair
25 Sep - 13 Oct	Hainan Airlines
18 Sep - 06 Oct	Ryanair

Also check the deals for one-way flights from Madrid to Osaka in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Osaka in September from 661€

Return flights