Cheapest return flights from Madrid to Istanbul in May from 107€

AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (IST) in May 2026 (see full year).

Return flights

06 May - 13 May Ryanair
06 May - 15 Jun Ryanair
06 May - 12 May Ryanair
06 May - 09 May Wizz Air UK
09 May - 12 May Wizz Air UK
11 May - 15 May Wizz Air UK
06 May - 08 May Ryanair
10 May - 13 May Ryanair
13 May - 15 May Ryanair
12 May - 27 May Wizz Air UK
07 May - 12 May Ryanair
19 May - 15 Jun Wizz Air
26 May - 03 Jun Ryanair
13 May - 03 Jun Wizz Air UK
12 May - 23 Jun Wizz Air UK
27 May - 06 Jun Ryanair
27 May - 04 Jun Ryanair
27 May - 02 Jun Ryanair
28 May - 03 Jun Air Serbia
31 May - 12 Jun Wizz Air Malta

Also check the deals for one-way flights from Madrid to Istanbul in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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