Cheapest return flights from Madrid to Istanbul in May from 146€

AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (IST) in May 2026 (see full year).

Return flights

03 May - 12 May Ryanair
27 May - 09 Jun Ryanair
26 May - 03 Jun Wizz Air UK
07 May - 13 May Pegasus Airlines direct
27 May - 10 Jun Ryanair
26 May - 13 Jun Wizz Air UK
26 May - 09 Jun Wizz Air UK
12 May - 19 May Wizz Air UK
02 May - 12 May Wizz Air UK
07 May - 12 May Wizz Air UK
27 May - 06 Jun Ryanair
02 May - 13 May Wizz Air UK
27 May - 31 May Ryanair
26 May - 02 Jun Wizz Air UK
05 May - 13 May Ryanair
06 May - 13 May Pegasus Airlines direct
27 May - 04 Jun Ryanair
06 May - 12 May easyJet
31 May - 09 Jun Ryanair
27 May - 03 Jun Ryanair

Also check the deals for one-way flights from Madrid to Istanbul in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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