AirHint found the following cheapest return flights from Madrid (MAD) to Guayaquil (GYE) in September 2026 (see full year).
Return flights
| 14 Sep - 14 Oct | Avianca | ||
| 10 Sep - 25 Sep | Avianca | ||
| 01 Sep - 23 Sep | Avianca | ||
| 01 Sep - 24 Sep | LATAM Airlines Group | ||
| 14 Sep - 14 Oct | Air Europa | direct | |
| 18 Sep - 29 Sep | American Airlines |
Also check the deals for one-way flights from Madrid to Guayaquil in September.
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