AirHint found the following cheapest return flights from Madrid (MAD) to Guayaquil (GYE) in May 2026 (see full year).

Return flights

18 May - 31 May	Avianca
14 May - 27 May	Avianca
01 May - 14 May	Avianca
21 May - 31 May	Avianca
15 May - 28 May	Avianca
01 May - 10 May	Avianca
01 May - 20 May	Avianca
08 May - 19 May	Avianca
22 May - 01 Jun	Avianca
01 May - 05 Jun	Air Europa	direct
01 May - 10 May	Air Europa	direct
21 May - 03 Jun	Iberia	direct
31 May - 14 Jun	LATAM Airlines Group
01 May - 15 May	Air Europa	direct
24 May - 07 Jun	Air Europa	direct
31 May - 14 Jun	Iberia	direct
30 May - 14 Jun	Air France
30 May - 13 Jun	LATAM Airlines Group
29 May - 06 Jun	Avianca

Also check the deals for one-way flights from Madrid to Guayaquil in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Guayaquil in May from 553€

Return flights