AirHint found the following cheapest return flights from Madrid (MAD) to Guayaquil (GYE) in December 2025 (see full year).

Return flights

04 Dec - 11 Dec	easyJet
30 Dec - 24 Jan	Avianca
05 Dec - 10 Dec	easyJet
07 Dec - 15 Jan	Ryanair
12 Dec - 21 Jan	TAP
12 Dec - 12 Jan	TAP
12 Dec - 13 Jan	TAP
11 Dec - 12 Jan	TAP
11 Dec - 13 Jan	TAP
12 Dec - 15 Jan	TAP
30 Dec - 12 Jan	Iberia Express
31 Dec - 12 Jan	Iberia
05 Dec - 13 Dec	easyJet
09 Dec - 30 Dec	Ryanair
01 Dec - 31 Dec	Ryanair
01 Dec - 12 Dec	Ryanair
01 Dec - 13 Dec	Ryanair
25 Dec - 31 Dec	Avianca
07 Dec - 28 Dec	Ryanair
08 Dec - 14 Dec	TAP

Also check the deals for one-way flights from Madrid to Guayaquil in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Guayaquil in December from 692€

Return flights