AirHint found the following cheapest return flights from Madrid (MAD) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

03 Dec - 07 Dec	TAP
03 Dec - 08 Dec	TAP
02 Dec - 09 Dec	TAP
01 Dec - 08 Dec	TAP
02 Dec - 08 Dec	TAP
02 Dec - 11 Dec	TAP
10 Dec - 26 Jan	TAP
25 Dec - 28 Jan	Iberia
01 Dec - 31 Dec	Royal Air Maroc
01 Dec - 14 Dec	Royal Air Maroc
09 Dec - 12 Dec	Royal Air Maroc
04 Dec - 14 Dec	TAP
27 Dec - 27 Jan	TAP
27 Dec - 30 Jan	Iberia
27 Dec - 29 Jan	Iberia
24 Dec - 31 Jan	TAP
24 Dec - 26 Jan	TAP
15 Dec - 21 Jan	Royal Air Maroc
16 Dec - 23 Jan	Royal Air Maroc
15 Dec - 14 Jan	Royal Air Maroc

Also check the deals for one-way flights from Madrid to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Sao Paulo

Cheap car rent in Sao Paulo

Cheapest return flights from Madrid to Sao Paulo in December from 509€

Return flights