AirHint found the following cheapest return flights from Madrid (MAD) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

01 Dec - 10 Dec	Royal Air Maroc
01 Dec - 09 Dec	Royal Air Maroc
02 Dec - 10 Dec	Royal Air Maroc
02 Dec - 11 Dec	Iberia
05 Dec - 08 Dec	TAP
01 Dec - 09 Dec	LATAM Airlines Group	direct
02 Dec - 12 Dec	Iberia
02 Dec - 24 Jan	Delta
01 Dec - 10 Dec	LATAM Airlines Group	direct
08 Dec - 31 Jan	LATAM Airlines Group	direct
05 Dec - 12 Dec	Iberia
04 Dec - 11 Dec	Iberia
25 Dec - 27 Jan	Iberia
31 Dec - 18 Jan	Delta
11 Dec - 25 Jan	Air Canada
06 Dec - 18 Jan	Delta
09 Dec - 24 Jan	Delta
02 Dec - 24 Jan	Iberia	direct
15 Dec - 31 Jan	Ryanair
11 Dec - 27 Jan	ITA Airways

Also check the deals for one-way flights from Madrid to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Sao Paulo in December from 560€

Return flights