AirHint found the following cheapest return flights from Madrid (MAD) to Cairo (CAI) in September 2025 (see full year).

Return flights

29 Sep - 03 Oct	Wizz Air Malta
23 Sep - 03 Oct	Wizz Air Malta
23 Sep - 30 Sep	Wizz Air Malta
25 Sep - 03 Oct	Wizz Air Malta
27 Sep - 03 Oct	Iberia
20 Sep - 29 Sep	Iberia
25 Sep - 30 Sep	Wizz Air Malta
30 Sep - 07 Oct	Wizz Air Malta
15 Sep - 30 Sep	Wizz Air Malta
26 Sep - 03 Oct	Wizz Air Malta
28 Sep - 03 Oct	Wizz Air Malta
20 Sep - 03 Oct	Wizz Air Malta
10 Sep - 19 Sep	Wizz Air Malta
16 Sep - 29 Sep	Iberia
21 Sep - 29 Sep	Wizz Air Malta
22 Sep - 29 Sep	Wizz Air Malta
25 Sep - 01 Oct	Wizz Air Malta
27 Sep - 11 Oct	Iberia
12 Sep - 19 Sep	Ryanair
26 Sep - 29 Sep	Wizz Air Malta

Also check the deals for one-way flights from Madrid to Cairo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Cairo in September from 215€

Return flights