AirHint found the following cheapest return flights from Madrid (MAD) to Asuncion (ASU) in December 2025 (see full year).

Return flights

29 Dec - 29 Jan	LATAM Airlines Group
02 Dec - 28 Jan	LATAM Airlines Group
01 Dec - 14 Dec	LATAM Airlines Group
04 Dec - 11 Dec	TAP
24 Dec - 24 Jan	Avianca
27 Dec - 24 Jan	LATAM Airlines Group
06 Dec - 30 Jan	LATAM Airlines Group
10 Dec - 24 Jan	easyJet
23 Dec - 21 Jan	LATAM Airlines Group
09 Dec - 13 Jan	Air Europa
22 Dec - 22 Jan	LATAM Airlines Group
03 Dec - 24 Dec	Air Europa
07 Dec - 07 Jan	LATAM Airlines Group
09 Dec - 26 Dec	LATAM Airlines Group
14 Dec - 31 Dec	LATAM Airlines Group
13 Dec - 20 Dec	Ryanair
19 Dec - 27 Dec	Avianca
21 Dec - 28 Dec	Ryanair

Also check the deals for one-way flights from Madrid to Asuncion in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Asuncion in December from 833€

Return flights