AirHint found the following cheapest return flights from Madrid (MAD) to Asuncion (ASU) in December 2025 (see full year).

Return flights

31 Dec - 22 Jan	LATAM Airlines Group
04 Dec - 08 Dec	LATAM Airlines Group
07 Dec - 14 Dec	Azul Airlines
29 Dec - 23 Jan	LATAM Airlines Group
29 Dec - 25 Jan	LATAM Airlines Group
01 Dec - 14 Dec	LATAM Airlines Group
31 Dec - 27 Jan	Avianca
08 Dec - 24 Dec	LATAM Airlines Group
04 Dec - 31 Dec	Azul Airlines
02 Dec - 16 Dec	Azul Airlines
31 Dec - 18 Jan	Avianca
04 Dec - 28 Dec	Azul Airlines
24 Dec - 25 Jan	LATAM Airlines Group
31 Dec - 20 Jan	Avianca
09 Dec - 11 Dec	Azul Airlines
06 Dec - 14 Dec	Azul Airlines
01 Dec - 24 Jan	Azul Airlines
04 Dec - 20 Jan	Azul Airlines
01 Dec - 31 Dec	Azul Airlines
15 Dec - 29 Jan	LATAM Airlines Group

Also check the deals for one-way flights from Madrid to Asuncion in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Asuncion in December from 780€

Return flights