AirHint found the following cheapest return flights from Madrid (MAD) to Asuncion (ASU) in October 2025 (see full year).

Return flights

06 Oct - 12 Oct	TAP
02 Oct - 20 Oct	LATAM Airlines Group
07 Oct - 21 Oct	TAP
27 Oct - 17 Nov	Air Europa	direct
06 Oct - 31 Oct	TAP
23 Oct - 03 Nov	Avianca
26 Oct - 16 Nov	Ryanair
09 Oct - 26 Oct	LATAM Airlines Group
16 Oct - 31 Oct	LATAM Airlines Group
20 Oct - 02 Nov	Air Europa	direct
23 Oct - 05 Nov	Air Europa	direct
26 Oct - 17 Nov	Ryanair
11 Oct - 08 Nov	Avianca
23 Oct - 20 Nov	Avianca
23 Oct - 12 Nov	Air Europa	direct
23 Oct - 19 Nov	Air Europa	direct
06 Oct - 16 Oct	TAP
03 Oct - 19 Oct	Ryanair
10 Oct - 17 Oct	Iberia
09 Oct - 24 Oct	Wizz Air Malta

Also check the deals for one-way flights from Madrid to Asuncion in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Asuncion in October from 848€

Return flights