AirHint found the following cheapest return flights from London (LON) to Santiago (SCL) in December 2025 (see full year).

Return flights

27 Dec - 27 Jan	Air Europa
25 Dec - 27 Jan	Delta
24 Dec - 27 Jan	Delta
30 Dec - 25 Jan	easyJet
23 Dec - 27 Jan	Delta
31 Dec - 22 Jan	Ryanair
26 Dec - 11 Jan	Delta
26 Dec - 17 Jan	Delta
24 Dec - 28 Dec	Delta
23 Dec - 18 Jan	Delta
29 Dec - 11 Jan	Delta
24 Dec - 26 Dec	Delta
25 Dec - 30 Dec	Delta
24 Dec - 31 Dec	Ryanair
23 Dec - 27 Dec	Delta
23 Dec - 30 Dec	Air Canada
22 Dec - 26 Dec	Iberia
22 Dec - 22 Dec	LATAM Airlines Group
22 Dec - 26 Dec	British Airways	direct

Also check the deals for one-way flights from London to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in December from 973€

Return flights