AirHint found the following cheapest return flights from London (LON) to Santiago (SCL) in December 2025 (see full year).

Return flights

02 Dec - 05 Dec	Wizz Air Malta
01 Dec - 08 Dec	Air France
01 Dec - 14 Dec	KLM
04 Dec - 29 Jan	Vueling Airlines
01 Dec - 12 Dec	Iberia For Level
03 Dec - 15 Dec	Virgin Atlantic
06 Dec - 22 Dec	Ryanair
03 Dec - 07 Dec	Ryanair
06 Dec - 14 Dec	easyJet
08 Dec - 14 Dec	Virgin Atlantic
13 Dec - 23 Jan	Vueling Airlines
03 Dec - 23 Dec	Iberia For Level
31 Dec - 20 Jan	Vueling Airlines
01 Dec - 26 Jan	Air Canada
29 Dec - 31 Jan	Ryanair
08 Dec - 21 Jan	Air Canada
11 Dec - 12 Jan	Vueling Airlines
25 Dec - 31 Jan	Vueling Airlines
08 Dec - 14 Jan	Air Canada
24 Dec - 31 Jan	Ryanair

Also check the deals for one-way flights from London to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in December from 772€

Return flights