AirHint found the following cheapest return flights from Lisbon (LIS) to Santiago (SCL) in December 2025 (see full year).

Return flights

26 Dec - 27 Jan	British Airways
09 Dec - 27 Jan	British Airways
10 Dec - 27 Jan	British Airways
16 Dec - 27 Jan	Iberia
15 Dec - 27 Jan	Iberia
14 Dec - 27 Jan	Iberia
08 Dec - 19 Dec	Iberia
10 Dec - 20 Jan	Iberia
28 Dec - 31 Jan	Iberia
29 Dec - 31 Jan	Iberia
25 Dec - 06 Jan	Air Canada
05 Dec - 26 Dec	British Airways

Also check the deals for one-way flights from Lisbon to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Lisbon to Santiago in December from 772€

Return flights