AirHint found the following cheapest return flights from London (LHR) to Santiago (SCL) in September 2025 (see full year).

Return flights

14 Sep - 04 Oct	Iberia
14 Sep - 30 Sep	Iberia
08 Sep - 30 Sep	Air France
16 Sep - 24 Sep	TAP
10 Sep - 23 Oct	Avianca
25 Sep - 28 Sep	TAP
25 Sep - 02 Oct	TAP
13 Sep - 26 Sep	Avianca
10 Sep - 24 Sep	Avianca
04 Sep - 28 Sep	Avianca
24 Sep - 06 Oct	Avianca
25 Sep - 07 Oct	Avianca
15 Sep - 23 Sep	Avianca
05 Sep - 26 Sep	Avianca
11 Sep - 25 Sep	Avianca
15 Sep - 15 Oct	Avianca
16 Sep - 15 Oct	Avianca
15 Sep - 14 Oct	Avianca
17 Sep - 15 Oct	Avianca
16 Sep - 14 Oct	Avianca

Also check the deals for one-way flights from London to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in September from 803€

Return flights