AirHint found the following cheapest return flights from London (LHR) to Santiago (SCL) in September 2025 (see full year).

Return flights

25 Sep - 16 Oct	Avianca
25 Sep - 14 Oct	Avianca
25 Sep - 05 Oct	Avianca
26 Sep - 03 Oct	Avianca
26 Sep - 28 Sep	Virgin Atlantic
25 Sep - 04 Oct	Avianca
26 Sep - 04 Oct	Avianca
25 Sep - 30 Sep	Avianca
24 Sep - 28 Sep	Avianca
25 Sep - 29 Sep	Avianca
25 Sep - 28 Sep	Avianca
25 Sep - 02 Oct	Avianca
29 Sep - 03 Oct	Finnair
27 Sep - 04 Oct	Avianca
28 Sep - 15 Oct	Avianca
27 Sep - 28 Sep	Air France
23 Sep - 24 Sep	Delta
28 Sep - 29 Sep	Avianca
22 Sep - 23 Sep	Avianca
26 Sep - 30 Sep	Delta

Also check the deals for one-way flights from London to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in September from 843€

Return flights