AirHint found the following cheapest return flights from London (LHR) to Santiago (SCL) in October 2025 (see full year).

Return flights

28 Oct - 04 Nov	Air Canada
06 Oct - 14 Oct	Air France
06 Oct - 12 Oct	Air France
29 Oct - 12 Nov	Lufthansa
29 Oct - 07 Nov	Lufthansa
28 Oct - 07 Nov	Lufthansa
28 Oct - 06 Nov	Lufthansa
30 Oct - 06 Nov	Lufthansa
29 Oct - 25 Nov	Lufthansa
25 Oct - 01 Nov	Lufthansa
28 Oct - 10 Nov	Lufthansa
05 Oct - 12 Oct	Air France
14 Oct - 21 Oct	Avianca
09 Oct - 16 Oct	Avianca
09 Oct - 12 Nov	Avianca
09 Oct - 20 Oct	Avianca
01 Oct - 09 Oct	KLM
06 Oct - 11 Oct	Virgin Atlantic
06 Oct - 17 Oct	Virgin Atlantic
13 Oct - 17 Oct	Brussels Airlines

Also check the deals for one-way flights from London to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in October from 799€

Return flights