AirHint found the following cheapest return flights from London (LCY) to Santiago (SCL) in September 2025 (see full year).

Return flights

08 Sep - 19 Sep	KLM
10 Sep - 17 Sep	KLM
09 Sep - 16 Sep	KLM
08 Sep - 07 Oct	KLM
17 Sep - 24 Sep	KLM
11 Sep - 25 Sep	ITA Airways
01 Sep - 30 Sep	KLM
18 Sep - 25 Oct	Air Dolomiti
15 Sep - 22 Sep	Delta
05 Sep - 21 Sep	Delta
15 Sep - 21 Sep	Delta
17 Sep - 15 Oct	Delta
12 Sep - 25 Sep	KLM
18 Sep - 23 Oct	Air Dolomiti
01 Sep - 31 Oct	KLM
30 Sep - 25 Oct	Delta
25 Sep - 30 Oct	KLM
29 Sep - 08 Oct	Delta
17 Sep - 08 Oct	KLM
18 Sep - 06 Oct	KLM

Also check the deals for one-way flights from London to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in September from 1033€

Return flights