AirHint found the following cheapest return flights from London (LCY) to Santiago (SCL) in October 2025 (see full year).

Return flights

09 Oct - 12 Oct	KLM
27 Oct - 11 Nov	ITA Airways
29 Oct - 06 Nov	KLM
16 Oct - 30 Oct	ITA Airways
30 Oct - 13 Nov	KLM
27 Oct - 25 Nov	Delta
30 Oct - 06 Nov	KLM
10 Oct - 24 Oct	ITA Airways
15 Oct - 20 Oct	ITA Airways
14 Oct - 09 Nov	KLM
30 Oct - 28 Nov	KLM
29 Oct - 12 Nov	KLM
27 Oct - 09 Nov	KLM
14 Oct - 20 Oct	ITA Airways
29 Oct - 13 Nov	ITA Airways
01 Oct - 14 Oct	KLM
17 Oct - 30 Oct	KLM
05 Oct - 18 Oct	KLM
23 Oct - 30 Oct	KLM
02 Oct - 09 Oct	Delta

Also check the deals for one-way flights from London to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in October from 1030€

Return flights