AirHint found the following cheapest return flights from London (LCY) to Prague (PRG) in September 2025 (see full year).

Return flights

30 Sep - 03 Oct	KLM
30 Sep - 31 Oct	KLM
27 Sep - 01 Oct	KLM
29 Sep - 02 Oct	KLM
30 Sep - 04 Oct	KLM
27 Sep - 04 Oct	KLM
27 Sep - 30 Sep	KLM
27 Sep - 02 Oct	KLM
29 Sep - 04 Oct	KLM
29 Sep - 17 Oct	KLM
26 Sep - 30 Sep	KLM
26 Sep - 03 Oct	KLM
24 Sep - 30 Sep	KLM
19 Sep - 25 Sep	KLM
20 Sep - 30 Sep	KLM
20 Sep - 23 Sep	KLM
23 Sep - 30 Sep	KLM
18 Sep - 23 Sep	KLM
23 Sep - 27 Sep	KLM
26 Sep - 27 Sep	KLM

Also check the deals for one-way flights from London to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague

Cheapest return flights from London to Prague in September from 201€

Return flights