AirHint found the following cheapest return flights from London (LCY) to Prague (PRG) in September 2025 (see full year).

Return flights

02 Sep - 17 Sep	ITA Airways
23 Sep - 26 Sep	KLM
01 Sep - 04 Sep	KLM
05 Sep - 10 Sep	KLM
01 Sep - 10 Sep	KLM
02 Sep - 10 Sep	KLM
03 Sep - 10 Sep	KLM
22 Sep - 25 Sep	KLM
01 Sep - 30 Sep	KLM
02 Sep - 05 Sep	KLM
28 Sep - 07 Oct	KLM
24 Sep - 15 Oct	KLM
23 Sep - 14 Oct	KLM
30 Sep - 21 Oct	KLM
29 Sep - 02 Oct	KLM
17 Sep - 08 Oct	KLM
27 Sep - 08 Oct	KLM
17 Sep - 01 Oct	KLM
21 Sep - 01 Oct	KLM
16 Sep - 07 Oct	KLM

Also check the deals for one-way flights from London to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Prague in September from 197€

Return flights