AirHint found the following cheapest return flights from Osaka (ITM) to Madrid (MAD) in September 2025 (see full year).

Return flights

25 Sep - 07 Oct	Iberia
24 Sep - 07 Oct	Japan Airlines
03 Sep - 08 Sep	Lufthansa
03 Sep - 10 Sep	Lufthansa
15 Sep - 01 Oct	Japan Airlines
01 Sep - 10 Sep	Lufthansa
01 Sep - 07 Sep	Lufthansa
13 Sep - 27 Sep	ANA
01 Sep - 17 Sep	Lufthansa
17 Sep - 23 Sep	Lufthansa
28 Sep - 14 Oct	Lufthansa
20 Sep - 24 Sep	Lufthansa
19 Sep - 23 Sep	Lufthansa
23 Sep - 30 Sep	Japan Airlines
28 Sep - 13 Oct	Japan Airlines
26 Sep - 03 Oct	Lufthansa
06 Sep - 11 Oct	Lufthansa
06 Sep - 18 Oct	Lufthansa

Also check the deals for one-way flights from Osaka to Madrid in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Osaka to Madrid in September from 1336€

Return flights