AirHint found the following cheapest return flights from Istanbul (IST) to Prague (PRG) in May 2026 (see full year).

Return flights

04 May - 08 May	Air Serbia
24 May - 30 May	Air Serbia
16 May - 19 May	Air Serbia
21 May - 26 May	Air Serbia
22 May - 30 May	Air Serbia
26 May - 30 May	Air Serbia
31 May - 04 Jun	Air Serbia
08 May - 11 May	Air Serbia
06 May - 17 May	SKY express
13 May - 31 May	SKY express
20 May - 31 May	Wizz Air UK
25 May - 14 Jun	SKY express
25 May - 07 Jun	SKY express
30 May - 14 Jun	SKY express
30 May - 07 Jun	SKY express
20 May - 07 Jun	SKY express
31 May - 14 Jun	Fly One
29 May - 14 Jun	Fly One
29 May - 07 Jun	Fly One
24 May - 07 Jun	Fly One

Also check the deals for one-way flights from Istanbul to Prague in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Prague in May from 179€

Return flights