AirHint found the following cheapest return flights from Istanbul (IST) to Prague (PRG) in May 2026 (see full year).

Return flights

28 May - 31 May	Lufthansa
26 May - 29 May	Wizz Air UK
02 May - 08 May	Turkish Airlines	direct
23 May - 30 May	Wizz Air UK
21 May - 24 May	Turkish Airlines	direct
26 May - 29 May	Turkish Airlines	direct
28 May - 31 May	Turkish Airlines	direct
01 May - 03 May	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Prague in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Prague in May from 214€

Return flights