AirHint found the following cheapest return flights from Istanbul (IST) to Madrid (MAD) in October 2026 (see full year).

Return flights

06 Oct - 13 Oct	Pegasus Airlines
06 Oct - 13 Oct	Pegasus Airlines	direct
21 Oct - 28 Oct	Wizz Air UK
28 Oct - 04 Nov	AJet
10 Oct - 12 Oct	Wizz Air
24 Oct - 29 Oct	AJet
10 Oct - 02 Nov	Pegasus Airlines
31 Oct - 22 Nov	Air Serbia
31 Oct - 05 Nov	Air France
12 Oct - 17 Oct	Pegasus Airlines
31 Oct - 05 Nov	Air Europa	direct
31 Oct - 22 Nov	Air Europa	direct
11 Oct - 23 Oct	SKY express
18 Oct - 23 Oct	SKY express
28 Oct - 04 Nov	Air Europa	direct
11 Oct - 15 Oct	SKY express
24 Oct - 29 Oct	Air Europa	direct
10 Oct - 02 Nov	Air Europa	direct
28 Oct - 01 Nov	AJet

Also check the deals for one-way flights from Istanbul to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Madrid in October from 155€

Return flights