AirHint found the following cheapest return flights from Istanbul (IST) to Cape Town (CPT) in September 2025 (see full year).

Return flights

27 Sep - 05 Oct	Pegasus Airlines
26 Sep - 13 Oct	Air Arabia
22 Sep - 26 Sep	Ethiopian Airlines
23 Sep - 29 Sep	KLM
20 Sep - 29 Sep	KLM
23 Sep - 30 Sep	KLM
22 Sep - 28 Sep	flyadeal
22 Sep - 30 Sep	KLM
20 Sep - 23 Sep	flyadeal
21 Sep - 23 Sep	flyadeal
20 Sep - 30 Sep	flyadeal
19 Sep - 22 Sep	Flynas

Also check the deals for one-way flights from Istanbul to Cape Town in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Cape Town in September from 632€

Return flights