AirHint found the following cheapest return flights from Nis (INI) to Istanbul (IST) in April 2026 (see full year).

Return flights

07 Apr - 11 Apr	Air Serbia	direct
04 Apr - 07 Apr	Air Serbia	direct
18 Apr - 21 Apr	Air Serbia	direct
25 Apr - 28 Apr	Air Serbia	direct
15 Apr - 18 Apr	Air Serbia
22 Apr - 25 Apr	Air Serbia
01 Apr - 04 Apr	Air Serbia
29 Apr - 02 May	Air Serbia
07 Apr - 10 Apr	Turkish Airlines

Also check the deals for one-way flights from Nis to Istanbul in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Nis to Istanbul in April from 145€

Return flights