Cheapest return flights from Indianapolis to Rome in September from 451€

AirHint found the following cheapest return flights from Indianapolis (IND) to Rome (FCO) in September 2025 (see full year).

Return flights

05 Sep - 14 Sep Spirit Airlines
04 Sep - 11 Sep Spirit Airlines
10 Sep - 20 Sep Spirit Airlines
04 Sep - 12 Sep Spirit Airlines
08 Sep - 30 Sep Spirit Airlines
12 Sep - 20 Sep Spirit Airlines
20 Sep - 03 Oct Spirit Airlines
23 Sep - 30 Sep United
11 Sep - 18 Sep United
08 Sep - 15 Sep United
14 Sep - 21 Sep United
29 Sep - 06 Oct United
26 Sep - 03 Oct United

Also check the deals for one-way flights from Indianapolis to Rome in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome

Feel free to contact us with any feedback or request another flight research.