AirHint found the following cheapest return flights from Houston (IAH) to Panama City (PTY) in May 2026 (see full year).

Return flights

26 May - 01 Jun	Spirit Airlines
21 May - 26 May	Spirit Airlines
22 May - 30 May	Avianca
22 May - 25 May	Avianca
22 May - 30 May	United	direct
21 May - 26 May	United	direct
26 May - 01 Jun	United	direct
22 May - 25 May	United	direct
14 May - 21 May	United	direct
18 May - 25 May	United	direct
20 May - 27 May	United	direct
15 May - 22 May	United	direct

Also check the deals for one-way flights from Houston to Panama City in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Panama City in May from 410€

Return flights