AirHint found the following cheapest return flights from Houston (IAH) to Istanbul (IST) in May 2026 (see full year).

Return flights

12 May - 20 May	Spirit Airlines
01 May - 15 May	Spirit Airlines
13 May - 27 May	Spirit Airlines
01 May - 12 May	Spirit Airlines
02 May - 16 May	Spirit Airlines
07 May - 22 May	Spirit Airlines
19 May - 25 May	KLM
19 May - 02 Jun	KLM
31 May - 08 Jun	WestJet
28 May - 01 Jun	KLM
13 May - 27 May	Turkish Airlines	direct
25 May - 28 May	KLM
25 May - 27 May	KLM
22 May - 05 Jun	KLM
22 May - 03 Jun	KLM
27 May - 13 Jun	Spirit Airlines
29 May - 23 Jun	KLM
29 May - 25 Jun	KLM
19 May - 02 Jun	Turkish Airlines	direct
22 May - 03 Jun	Turkish Airlines	direct

Also check the deals for one-way flights from Houston to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Istanbul in May from 581€

Return flights