Cheapest return flights from Houston to Panama City in September from 407€

AirHint found the following cheapest return flights from Houston (HOU) to Panama City (PTY) in September 2025 (see full year).

Return flights

04 Sep - 16 Sep Spirit Airlines
23 Sep - 30 Sep Spirit Airlines
18 Sep - 21 Sep Spirit Airlines
13 Sep - 27 Sep Spirit Airlines
25 Sep - 05 Oct Spirit Airlines
17 Sep - 20 Sep Avianca
04 Sep - 16 Sep United direct
23 Sep - 30 Sep United direct
25 Sep - 05 Oct United direct
13 Sep - 27 Sep United direct
18 Sep - 21 Sep United direct

Also check the deals for one-way flights from Houston to Panama City in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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