AirHint found the following cheapest return flights from Houston (HOU) to Panama City (PTY) in August 2025 (see full year).

Return flights

13 Aug - 20 Aug	Spirit Airlines
11 Aug - 18 Aug	Spirit Airlines
10 Aug - 17 Aug	Spirit Airlines
07 Aug - 14 Aug	Spirit Airlines
26 Aug - 30 Aug	Spirit Airlines
25 Aug - 01 Sep	Spirit Airlines
08 Aug - 15 Aug	Spirit Airlines
28 Aug - 01 Sep	Frontier Airlines
20 Aug - 31 Aug	Spirit Airlines
08 Aug - 11 Aug	Spirit Airlines
06 Aug - 09 Aug	Spirit Airlines
01 Aug - 05 Aug	Spirit Airlines
25 Aug - 01 Sep	United	direct
28 Aug - 02 Sep	United	direct
28 Aug - 01 Sep	United	direct

Also check the deals for one-way flights from Houston to Panama City in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Panama City in August from 369€

Return flights