AirHint found the following cheapest return flights from Houston (HOU) to Panama City (PTY) in August 2025 (see full year).

Return flights

15 Aug - 22 Aug	Spirit Airlines
05 Aug - 08 Aug	Spirit Airlines
29 Aug - 06 Sep	Spirit Airlines
01 Aug - 04 Aug	Spirit Airlines
29 Aug - 02 Sep	Spirit Airlines
28 Aug - 01 Sep	Spirit Airlines
20 Aug - 31 Aug	Spirit Airlines
20 Aug - 31 Aug	United	direct
31 Aug - 07 Sep	United	direct
29 Aug - 06 Sep	United	direct
15 Aug - 22 Aug	United	direct
28 Aug - 01 Sep	United	direct
29 Aug - 02 Sep	United	direct
20 Aug - 23 Aug	United

Also check the deals for one-way flights from Houston to Panama City in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Panama City in August from 374€

Return flights