AirHint found the following cheapest return flights from Houston (HOU) to Panama City (PTY) in July 2025 (see full year).

Return flights

26 Jul - 15 Aug	Spirit Airlines
15 Jul - 17 Jul	Spirit Airlines
17 Jul - 21 Jul	Spirit Airlines
20 Jul - 24 Jul	Spirit Airlines
23 Jul - 02 Aug	Spirit Airlines
14 Jul - 17 Jul	Spirit Airlines
03 Jul - 13 Aug	Avianca
12 Jul - 13 Jul	Frontier Airlines
05 Jul - 12 Jul	Spirit Airlines
06 Jul - 13 Jul	Avianca
23 Jul - 02 Aug	United	direct
03 Jul - 13 Aug	United	direct
12 Jul - 13 Jul	United	direct
05 Jul - 12 Jul	United	direct
06 Jul - 13 Jul	United	direct

Also check the deals for one-way flights from Houston to Panama City in July.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Panama City in July from 363€

Return flights