Cheapest return flights from Houston to Panama City in April from 442€

Best time to book flights for Houston (HOU) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Houston (HOU) to Panama City (PTY) in April 2025 (see full year).

Return flights

23 Apr - 18 May Frontier Airlines
30 Apr - 04 May Spirit Airlines
28 Apr - 05 May Spirit Airlines
17 Apr - 22 Apr Spirit Airlines
17 Apr - 21 Apr Spirit Airlines
04 Apr - 06 Apr Spirit Airlines
10 Apr - 21 Apr Spirit Airlines
06 Apr - 12 Apr Spirit Airlines
07 Apr - 14 Apr Spirit Airlines
25 Apr - 02 May Avianca
06 Apr - 13 Apr Avianca
23 Apr - 18 May United direct
25 Apr - 02 May United direct
07 Apr - 14 Apr United direct
17 Apr - 21 Apr United direct
17 Apr - 22 Apr United direct

Also check the deals for one-way flights from Houston to Panama City in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City