AirHint found the following cheapest return flights from Houston (HOU) to Milano (MXP) in September 2025 (see full year).

Return flights

20 Sep - 27 Sep	Frontier Airlines
05 Sep - 20 Sep	Spirit Airlines
03 Sep - 12 Sep	Spirit Airlines
16 Sep - 23 Sep	Turkish Airlines
05 Sep - 07 Sep	Spirit Airlines
24 Sep - 01 Oct	United
09 Sep - 16 Sep	United
15 Sep - 22 Sep	United
18 Sep - 25 Sep	United
27 Sep - 04 Oct	United
21 Sep - 28 Sep	United
12 Sep - 20 Sep	United

Also check the deals for one-way flights from Houston to Milano in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Milano in September from 522€

Return flights