AirHint found the following cheapest return flights from Houston (HOU) to Istanbul (IST) in May 2026 (see full year).

Return flights

06 May - 09 Jun	Spirit Airlines
05 May - 09 Jun	Spirit Airlines
13 May - 22 May	Austrian Airlines
06 May - 17 May	KLM
13 May - 27 May	KLM
10 May - 24 May	Frontier Airlines
26 May - 29 May	KLM
26 May - 30 May	KLM
06 May - 09 Jun	Turkish Airlines	direct
05 May - 09 Jun	Turkish Airlines	direct
18 May - 30 May	KLM
10 May - 24 May	Turkish Airlines	direct
29 May - 25 Jun	Spirit Airlines
13 May - 22 May	Turkish Airlines	direct
13 May - 27 May	Turkish Airlines	direct

Also check the deals for one-way flights from Houston to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Istanbul in May from 597€

Return flights