AirHint found the following cheapest return flights from Houston (HOU) to Istanbul (IST) in May 2026 (see full year).

Return flights

06 May - 13 May	Air Canada
07 May - 21 May	Spirit Airlines
01 May - 15 May	Spirit Airlines
07 May - 22 May	Spirit Airlines
13 May - 22 May	Air France
13 May - 27 May	Spirit Airlines
11 May - 24 May	KLM
12 May - 17 May	Air Canada
06 May - 09 May	Austrian Airlines
04 May - 07 May	KLM
24 May - 09 Jun	KLM
24 May - 08 Jun	KLM
26 May - 06 Jun	KLM
15 May - 14 Jun	British Airways
15 May - 14 Jun	Turkish Airlines	direct
29 May - 25 Jun	Spirit Airlines
24 May - 09 Jun	Turkish Airlines	direct
24 May - 08 Jun	Turkish Airlines	direct
26 May - 06 Jun	Turkish Airlines	direct

Also check the deals for one-way flights from Houston to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Istanbul in May from 525€

Return flights