AirHint found the following cheapest return flights from Guayaquil (GYE) to Panama City (PTY) in August 2025 (see full year).

Return flights

07 Aug - 11 Aug	Avianca
16 Aug - 19 Aug	Avianca
06 Aug - 09 Aug	Avianca
13 Aug - 18 Aug	Avianca
20 Aug - 26 Aug	Avianca
25 Aug - 29 Aug	Avianca
25 Aug - 31 Aug	Avianca
10 Aug - 17 Aug	Avianca
06 Aug - 10 Aug	Avianca
04 Aug - 07 Aug	Avianca
25 Aug - 01 Sep	Avianca
25 Aug - 01 Sep	Copa	direct

Also check the deals for one-way flights from Guayaquil to Panama City in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Cheapest return flights from Guayaquil to Panama City in August from 254€

Return flights