AirHint found the following cheapest return flights from Guayaquil (GYE) to Panama City (PTY) in February 2026 (see full year).

Return flights

23 Feb - 28 Feb	Avianca
16 Feb - 23 Feb	Avianca
11 Feb - 19 Feb	Avianca
02 Feb - 05 Feb	Avianca
06 Feb - 17 Feb	Avianca
18 Feb - 21 Feb	Avianca
19 Feb - 25 Feb	Avianca
21 Feb - 01 Mar	Avianca
19 Feb - 01 Mar	Avianca
09 Feb - 18 Feb	Avianca
10 Feb - 16 Feb	Avianca
08 Feb - 12 Feb	Avianca
19 Feb - 01 Mar	Copa	direct
21 Feb - 01 Mar	Copa	direct

Also check the deals for one-way flights from Guayaquil to Panama City in February.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guayaquil to Panama City in February from 296€

Return flights