Cheapest return flights from Guayaquil to Panama City in December from 290€

AirHint found the following cheapest return flights from Guayaquil (GYE) to Panama City (PTY) in December 2025 (see full year).

Return flights

16 Dec - 19 Dec Avianca
05 Dec - 09 Dec Avianca
03 Dec - 07 Dec Avianca
09 Dec - 11 Dec Avianca
08 Dec - 10 Dec Avianca
09 Dec - 11 Dec Copa direct
08 Dec - 10 Dec Copa direct
03 Dec - 07 Dec Copa direct

Also check the deals for one-way flights from Guayaquil to Panama City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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