AirHint found the following cheapest return flights from Guayaquil (GYE) to Panama City (PTY) in November 2025 (see full year).

Return flights

14 Nov - 17 Nov	Avianca
28 Nov - 30 Nov	Avianca
16 Nov - 19 Nov	Avianca
28 Nov - 01 Dec	Avianca
26 Nov - 29 Nov	Avianca
08 Nov - 10 Nov	Avianca
24 Nov - 25 Nov	Avianca
09 Nov - 11 Nov	Avianca
14 Nov - 22 Nov	Avianca
11 Nov - 13 Nov	Avianca
07 Nov - 16 Nov	Avianca
28 Nov - 05 Dec	Avianca
22 Nov - 06 Dec	Avianca
24 Nov - 02 Dec	Avianca
28 Nov - 03 Dec	Avianca
28 Nov - 01 Dec	Copa	direct
22 Nov - 22 Dec	Avianca
28 Nov - 05 Dec	Copa	direct
21 Nov - 21 Dec	Avianca
27 Nov - 01 Dec	Copa	direct

Also check the deals for one-way flights from Guayaquil to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guayaquil to Panama City in November from 292€

Return flights