AirHint found the following cheapest return flights from Guatemala City (GUA) to Madrid (MAD) in October 2025 (see full year).

Return flights

12 Oct - 13 Nov	Spirit Airlines
22 Oct - 17 Nov	Spirit Airlines
07 Oct - 23 Oct	Spirit Airlines
13 Oct - 23 Oct	Spirit Airlines
24 Oct - 03 Nov	Frontier Airlines
31 Oct - 03 Nov	Avianca
30 Oct - 03 Nov	Avianca
28 Oct - 04 Nov	Avianca
09 Oct - 23 Oct	Spirit Airlines
06 Oct - 23 Oct	Spirit Airlines
22 Oct - 31 Oct	Spirit Airlines
19 Oct - 08 Nov	Copa
24 Oct - 08 Nov	Copa
08 Oct - 16 Oct	Spirit Airlines
19 Oct - 26 Oct	Volaris El Salvador
25 Oct - 31 Oct	Spirit Airlines
24 Oct - 31 Oct	Spirit Airlines
09 Oct - 16 Oct	Spirit Airlines
23 Oct - 06 Nov	Avianca
13 Oct - 10 Nov	Spirit Airlines

Also check the deals for one-way flights from Guatemala City to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guatemala City to Madrid in October from 583€

Return flights