AirHint found the following cheapest return flights from Greenville (GSP) to Antigua (ANU) in December 2025 (see full year).
Return flights
| 17 Dec - 22 Dec | United | ||
| 18 Dec - 22 Dec | United | ||
| 14 Dec - 19 Dec | Allegiant Air | ||
| 11 Dec - 15 Dec | Allegiant Air |
Also check the deals for one-way flights from Greenville to Antigua in December.
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