AirHint found the following cheapest return flights from Sao Paulo (GRU) to Madrid (MAD) in October 2025 (see full year).

Return flights

29 Oct - 10 Nov	TAP
24 Oct - 12 Nov	Avianca
20 Oct - 12 Nov	Avianca
29 Oct - 09 Nov	TAP
31 Oct - 10 Nov	TAP
29 Oct - 06 Nov	TAP
24 Oct - 07 Nov	TAP
23 Oct - 06 Nov	TAP
23 Oct - 21 Nov	TAP
20 Oct - 20 Nov	TAP
20 Oct - 26 Oct	Air China	direct
13 Oct - 20 Oct	Air China	direct
14 Oct - 26 Oct	Air China	direct
13 Oct - 26 Oct	Air China	direct
20 Oct - 30 Oct	Air China	direct
03 Oct - 12 Oct	Air China	direct
14 Oct - 23 Oct	Royal Air Maroc
20 Oct - 27 Oct	Air China	direct
17 Oct - 26 Oct	Air China	direct
22 Oct - 31 Oct	Avianca

Also check the deals for one-way flights from Sao Paulo to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Madrid in October from 498€

Return flights