AirHint found the following cheapest one-way flights from Sao Paulo (GRU) to Madrid (MAD) in October 2025 (see full year).

One-Way flights

24 Oct	Air China	direct
20 Oct	Air China	direct
21 Oct	Air China	direct
17 Oct	Air China	direct
27 Oct	Air China	direct
14 Oct	Air China	direct
28 Oct	Air China	direct
13 Oct	Air China	direct
10 Oct	Air China	direct
31 Oct	Air China	direct

Also check the deals for return flights from Sao Paulo to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Sao Paulo to Madrid in October from 208€

One-Way flights