AirHint found the following cheapest return flights from Guadalajara (GDL) to Panama City (PTY) in December 2025 (see full year).
Return flights
| 22 Dec - 23 Jan | Aeromexico | ||
| 23 Dec - 03 Jan | Aeromexico | ||
| 22 Dec - 02 Jan | Aeromexico | ||
| 22 Dec - 23 Jan | Copa | direct | |
| 23 Dec - 03 Jan | Copa | direct | |
| 22 Dec - 02 Jan | Copa | direct |
Also check the deals for one-way flights from Guadalajara to Panama City in December.
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