AirHint found the following cheapest return flights from Frankfurt (FRA) to Santiago (SCL) in May 2026 (see full year).

Return flights

18 May - 27 May	LATAM Airlines Group
05 May - 25 May	LATAM Airlines Group
12 May - 26 May	Delta
06 May - 13 May	Delta
04 May - 11 May	Delta
20 May - 12 Jun	LATAM Airlines Group
18 May - 12 Jun	LATAM Airlines Group
22 May - 07 Jun	Air France
14 May - 24 May	Delta
12 May - 24 May	Delta
09 May - 24 May	Turkish Airlines
13 May - 25 May	LATAM Airlines Group
19 May - 12 Jun	Air France
21 May - 12 Jun	Air France
26 May - 27 May	Delta
10 May - 21 Jun	LATAM Airlines Group
20 May - 20 Jun	Air France
21 May - 10 Jun	Lufthansa

Also check the deals for one-way flights from Frankfurt to Santiago in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Santiago in May from 722€

Return flights