AirHint found the following cheapest return flights from Frankfurt (FRA) to Santiago (SCL) in December 2025 (see full year).

Return flights

08 Dec - 19 Jan	Air Canada
07 Dec - 19 Jan	Air Canada
02 Dec - 09 Dec	Air Canada
08 Dec - 24 Dec	Air Canada
02 Dec - 15 Dec	Air Canada
01 Dec - 15 Dec	Air Canada
17 Dec - 15 Jan	Air Canada
03 Dec - 25 Dec	Delta
29 Dec - 22 Jan	Delta
01 Dec - 20 Dec	Air Canada
02 Dec - 20 Dec	Air Canada
29 Dec - 15 Jan	Delta
29 Dec - 16 Jan	Delta
29 Dec - 18 Jan	Delta
25 Dec - 22 Jan	Delta
24 Dec - 16 Jan	Delta
06 Dec - 18 Jan	Delta
03 Dec - 26 Dec	Delta
04 Dec - 22 Dec	Delta
15 Dec - 25 Dec	Air Canada

Also check the deals for one-way flights from Frankfurt to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Santiago in December from 688€

Return flights