AirHint found the following cheapest return flights from Frankfurt (FRA) to Santiago (SCL) in December 2025 (see full year).

Return flights

10 Dec - 28 Jan	Air Canada
07 Dec - 23 Dec	Delta
15 Dec - 31 Jan	Air Canada
29 Dec - 15 Jan	Delta
29 Dec - 18 Jan	Delta
12 Dec - 23 Jan	Iberia
24 Dec - 15 Jan	Delta
07 Dec - 27 Dec	Delta
12 Dec - 22 Jan	Iberia
16 Dec - 06 Jan	Air Canada
14 Dec - 15 Jan	Air Canada
31 Dec - 19 Jan	Air Canada
08 Dec - 28 Dec	Iberia
12 Dec - 25 Dec	Air Canada

Also check the deals for one-way flights from Frankfurt to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Santiago in December from 785€

Return flights