AirHint found the following cheapest return flights from Frankfurt (FRA) to Panama City (PTY) in September 2026 (see full year).

Return flights

22 Sep - 06 Oct	Air Europa
22 Sep - 08 Oct	Air Europa
19 Sep - 03 Oct	Air France
09 Sep - 26 Sep	Air Europa
10 Sep - 26 Sep	Air Europa
14 Sep - 28 Sep	Air Europa
15 Sep - 29 Sep	Air Europa
14 Sep - 29 Sep	Air Europa
07 Sep - 20 Sep	Air France
15 Sep - 30 Sep	Air Europa
07 Sep - 23 Sep	Air Europa
02 Sep - 18 Sep	United
01 Sep - 17 Sep	Air France
19 Sep - 09 Oct	Air France

Also check the deals for one-way flights from Frankfurt to Panama City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Panama City in September from 540€

Return flights