AirHint found the following cheapest return flights from Frankfurt (FRA) to Panama City (PTY) in May 2026 (see full year).

Return flights

11 May - 25 May	Air Europa
23 May - 06 Jun	Air Europa
30 May - 07 Jun	Air Europa
25 May - 06 Jun	Air Europa
25 May - 31 May	Air France
02 May - 21 May	Air Europa
24 May - 30 May	Air Europa
16 May - 29 May	Air Europa
16 May - 30 May	Air Europa
07 May - 17 May	Air Europa
09 May - 23 May	Air Europa
10 May - 23 May	Air Europa
17 May - 24 May	Air France
01 May - 30 Jun	Air France

Also check the deals for one-way flights from Frankfurt to Panama City in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Panama City in May from 543€

Return flights