AirHint found the following cheapest return flights from Frankfurt (FRA) to Panama City (PTY) in April 2026 (see full year).

Return flights

25 Apr - 16 May	Air Europa
24 Apr - 15 May	Air Europa
16 Apr - 30 Apr	Air Europa
16 Apr - 28 May	Air Europa
25 Apr - 03 May	Air Europa
17 Apr - 03 May	Air Europa
06 Apr - 27 Apr	United
06 Apr - 23 Apr	United
06 Apr - 18 May	United
18 Apr - 04 May	United
05 Apr - 17 May	KLM
04 Apr - 25 Apr	Turkish Airlines
09 Apr - 20 May	Turkish Airlines
02 Apr - 18 Apr	Iberia
09 Apr - 22 May	KLM
11 Apr - 24 Apr	Air France
06 Apr - 27 Apr	Condor	direct
02 Apr - 18 Apr	Condor	direct
06 Apr - 23 Apr	Condor	direct
16 Apr - 30 Apr	Condor	direct

Also check the deals for one-way flights from Frankfurt to Panama City in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Panama City in April from 517€

Return flights