AirHint found the following cheapest return flights from Frankfurt (FRA) to Panama City (PTY) in April 2026 (see full year).

Return flights

16 Apr - 23 Apr	Air Europa
13 Apr - 29 Apr	Air Europa
10 Apr - 25 Apr	Air Europa
17 Apr - 30 Apr	Air Europa
23 Apr - 07 May	Air Europa
24 Apr - 07 May	Air Europa
30 Apr - 16 May	Air Europa
27 Apr - 11 May	Air Europa
11 Apr - 24 Apr	Air Europa
24 Apr - 08 May	Air Europa
22 Apr - 04 May	Air Europa
11 Apr - 18 Apr	Air France
25 Apr - 09 May	Air France
18 Apr - 02 May	Air France
01 Apr - 22 Apr	United
01 Apr - 08 Apr	United
09 Apr - 16 Apr	United
03 Apr - 12 Apr	United
17 Apr - 02 May	United
17 Apr - 09 May	United

Also check the deals for one-way flights from Frankfurt to Panama City in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Panama City in April from 522€

Return flights