AirHint found the following cheapest return flights from Frankfurt (FRA) to Panama City (PTY) in December 2025 (see full year).

Return flights

04 Dec - 18 Dec	Condor	direct
01 Dec - 22 Dec	Condor	direct
31 Dec - 27 Jan	United
30 Dec - 15 Jan	United
29 Dec - 21 Jan	United
30 Dec - 17 Jan	United
15 Dec - 29 Dec	United
26 Dec - 18 Jan	United
26 Dec - 12 Jan	United
15 Dec - 25 Dec	United
12 Dec - 08 Jan	United
29 Dec - 08 Jan	United
15 Dec - 22 Dec	Condor	direct
24 Dec - 16 Jan	United
26 Dec - 08 Jan	Lufthansa
12 Dec - 22 Dec	United
16 Dec - 23 Dec	Air France
03 Dec - 19 Dec	Air Europa
15 Dec - 29 Dec	Condor	direct
15 Dec - 25 Dec	Condor	direct

Also check the deals for one-way flights from Frankfurt to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Cheapest return flights from Frankfurt to Panama City in December from 600€

Return flights