AirHint found the following cheapest return flights from Frankfurt (FRA) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

11 Sep - 22 Oct	KLM
12 Sep - 21 Oct	TAP
20 Sep - 20 Oct	TAP
30 Sep - 07 Oct	Ryanair
30 Sep - 09 Oct	Ryanair
26 Sep - 07 Oct	Ryanair
25 Sep - 17 Oct	Ryanair
29 Sep - 23 Oct	Ryanair
24 Sep - 17 Oct	LATAM Airlines Group	direct
14 Sep - 21 Sep	Delta
14 Sep - 27 Sep	Delta
15 Sep - 24 Sep	Delta
24 Sep - 30 Sep	Delta
13 Sep - 27 Sep	Delta
19 Sep - 25 Sep	Delta
16 Sep - 28 Sep	Delta
14 Sep - 23 Sep	Delta
23 Sep - 30 Sep	Delta
15 Sep - 29 Sep	Delta
25 Sep - 01 Oct	Delta

Also check the deals for one-way flights from Frankfurt to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Sao Paulo in September from 598€

Return flights