AirHint found the following cheapest return flights from Rome (FCO) to Istanbul (SAW) in September 2025 (see full year).

Return flights

27 Sep - 01 Oct	Wizz Air Malta
03 Sep - 15 Sep	Wizz Air Malta
27 Sep - 05 Oct	Wizz Air Malta
17 Sep - 24 Sep	Wizz Air Malta
08 Sep - 11 Sep	Wizz Air Malta
08 Sep - 18 Oct	Wizz Air Malta
18 Sep - 21 Sep	Wizz Air Malta
09 Sep - 13 Sep	Wizz Air Malta
10 Sep - 17 Sep	Wizz Air Malta
16 Sep - 27 Sep	Wizz Air
16 Sep - 26 Sep	Wizz Air
16 Sep - 23 Sep	Wizz Air
11 Sep - 21 Sep	easyJet
29 Sep - 01 Oct	Wizz Air Malta
24 Sep - 09 Oct	Wizz Air Malta
11 Sep - 11 Oct	easyJet
30 Sep - 03 Oct	Wizz Air Malta
22 Sep - 26 Oct	Wizz Air Malta
28 Sep - 05 Oct	Wizz Air Malta
27 Sep - 03 Oct	Ryanair

Also check the deals for one-way flights from Rome to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul

Cheapest return flights from Rome to Istanbul in September from 132€

Return flights