AirHint found the following cheapest return flights from Rome (FCO) to Guayaquil (GYE) in December 2025 (see full year).

Return flights

24 Dec - 03 Jan	Vueling Airlines
15 Dec - 25 Jan	Vueling Airlines
14 Dec - 20 Jan	Vueling Airlines
15 Dec - 08 Jan	LATAM Airlines Group
18 Dec - 10 Jan	Vueling Airlines
15 Dec - 09 Jan	Vueling Airlines
19 Dec - 10 Jan	Vueling Airlines
29 Dec - 10 Jan	Vueling Airlines
18 Dec - 09 Jan	Vueling Airlines
20 Dec - 10 Jan	Vueling Airlines

Also check the deals for one-way flights from Rome to Guayaquil in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Guayaquil in December from 1051€

Return flights