AirHint found the following cheapest return flights from Newark (EWR) to Guayaquil (GYE) in September 2025 (see full year).

Return flights

28 Sep - 06 Oct	Spirit Airlines
26 Sep - 28 Sep	Spirit Airlines
18 Sep - 28 Sep	Spirit Airlines
19 Sep - 27 Sep	Frontier Airlines
20 Sep - 28 Sep	Frontier Airlines
26 Sep - 10 Oct	Spirit Airlines
19 Sep - 29 Sep	Spirit Airlines
19 Sep - 26 Sep	Spirit Airlines
12 Sep - 19 Sep	LATAM Airlines Group
18 Sep - 30 Sep	Spirit Airlines
11 Sep - 22 Sep	Spirit Airlines
11 Sep - 04 Oct	Spirit Airlines
18 Sep - 22 Sep	Spirit Airlines
20 Sep - 04 Oct	Spirit Airlines

Also check the deals for one-way flights from Newark to Guayaquil in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Newark to Guayaquil in September from 381€

Return flights